Rejuran Skin Treatment Sydney

What is Rejuran?

Rejuran is one of the newest skinboosters to have been approved for use in Australia. It contains Polynucleotides derived from salmon DNA as the active ingredient, and has rejuvenating properties for the skin. Polynucleotides are biological molecules that play a role in tissue repair and regeneration. It has a wide range of effects when injected directly into the skin including stimulation of cellular activity and growth factors leading to stimulation of collagen, improvement in skin elasticity and repair of the damaged and ageing skin from within.

What is Rejuran Used For?

There are three Rejuran products currently available in Australia: Rejuran Healer, Rejuran i, and Rejuran S. All three products contain the same active ingredient (polynucleotide) but come in various viscosity.

  • Rejuran Healer is used for whole face rejuvenation to improve fine lines, skin texture, skin tone, and to reduce the effects of ageing and sun damage.
  • Rejuran i is a lower viscosity product that is used for more delicate skin such as the skin around the eyes to address crepiness, wrinkles and dark circles.
  • Rejuran S is a higher viscosity product used to improve the appearance of scars and acne marks.


Many patients notice initial improvement in skin texture, elasticity, and overall appearance within a few weeks after their 2nd session. These results continue to improve over the following months.

  • First session: Improved hydration of the skin
  • Second session: Improvement in skin elasticity
  • Third session: Reduced fine lines

How Many Treatments Do I Need?

In general, we encourage 2-3 initial treatments 2-4 weeks apart, and repeat as needed (as our skin continues to age) which for some may be 6 monthly, or for others 12 monthly.

It is important to find a skilled and experienced provider who is able to deliver the product into the accurate layer of the skin as maximal visible results are achieved when the product is delivered precisely into the intradermal layer of the skin.

Post Treatment Care: What Not to Do After Rejuran

  • Avoid touching or rubbing the treated area immediately after treatment as it could potentially introduce bacteria or irritate the injection sites.
  • Light makeup can be applied 24 hours post treatment but avoid heavy makeup that can irritate the skin for 3-4 days until the skin has settled down from multiple injection sites.
  • Avoid using products containing retinoids or other potentially irritating ingredients until redness or swelling has subsided post treatment.
  • Avoid taking blood thinning medications (e.g. buprofen, aspirin) or supplements (e.g. fish oil, vitamin E) for 3-4 days before treatment and for another 24-48 hrs post Rejuran injections, as they can increase the risk of bruising or bleeding at the injection sites.

It is important to consult with your Rejuran provider for personal post treatment instructions tailored to your specific needs and circumstances.

Combined Skin Treatments

At your consultation, our experienced team will explore the possibility of combining treatments to maximise your results and create a personalised plan to address your skin goals.

Like to know more about your treatment options? 

Email us at or contact us on (02) 8356 2888 to book your consultation.

Shape clinic team

Frequently Asked Questions (FAQs)

Is Rejuran a Filler?

Rejuran is very different from fillers. Most fillers are made up of crosslinked hyaluronic acid molecules which attract water and therefore are able to provide volume. Rejuran on the other hand is made up of polynucleotides which work by promoting skin regeneration at a cellular level and does not cause an increase in volume.

Is Rejuran Painful?

Perception of pain with Rejuran treatment can vary among individuals, however it is generally well tolerated with appropriate analgesia. Rejuran treatment involves delivery of the product directly into the skin involving a series of multiple small injections across the treatment area. At our clinic we ensure patients are appropriately numbed with prescription strength topical anaesthesia prior to treatment, and we may sometimes additionally use nitrous oxide anaesthesia if needed. Rejuran injections are administered using ultra fine needles which are thinner than those used for other common injectable treatments.

Is Rejuran Permanent?

The duration of results from Rejuran treatment can vary depending on factors such as age, lifestyle, and the severity of skin concerns being addressed. Rejuran aims to ‘heal’ the skin at a cellular level leading to improvement in skin health, however the ageing process and exogenous stress of our skin continues which is why it is difficult to answer exactly how long Rejuran lasts.

Rejuran Skin Treatment Sydney Enquiry

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